8/27 Do The Ebola Drugs Actually Work?
- 2nd drug recipient dies; if the drug is so great - why did this happen?
How Will We Know If The Ebola Drugs Worked
another ZMapp recipient had passed away,
impossible to know if the treatment helped the patients, did nothing, or delayed their course of recovery.
To truly determine the effectiveness of ZMapp, not statistically possible with an n of 6 in even the best of circumstances, the inclusion criteria and site conditions would have needed to be as standardized as possible
8/27 Medical Pot Appears To Ameliorate Hunger For Pain Pills
- 25% fewer OD deaths seen
Could Medical Marijuana Laws Cut Painkiller Deaths?
States that have legalized medical marijuana may be reaping an unintended benefit from easing up on restrictions: They appear to have nearly 25 percent fewer deaths from overdoses involving prescription painkillers
effect increased in the years after the laws were enacted, suggesting the laws themselves may cause the difference.
Duh: Its cheaper, easier to get, you don't have to look over your shoulder for cops. As long as you stick to smoking it, it's nearly impossible to acutely overdose. What's not to like?
8/27 Novo Nordisk Says: We Go It Alone; No Need For Major Acquisitions
Novo Nordisk CEO Has No Plans for Big Acquisitions
no plans whatsoever in buying anything larger than things that we can finance through our own cash
insulin market is big enough and growing fast enough that Novo Nordisk doesn't need to
Related: Novo Nordisk aims for 2016 Tresiba launch in U.S.
8/27 Pills, Schmills, Treat My Arthur-ituis With An Injection
Biologics have higher psoriatic arthritis adherence
A study of psoriatic arthritis patients found greater adherence among patients whose initial treatment was a biologic, compared to those who started with a non-biologic treatment
8/27 PhRMA Urges: Off Label Promo Is Corporate Freedom Of Speech; Urges Dismissal Of Intergrilin Whistleblower
PhRMA Urges Court to Reject Off-Label Promotion Case
unapproved but fully legal uses of many FDA-approved prescription medicines to treat patients makes it critical that healthcare professionals have access to accurate, comprehensive, and current information about such uses
8/27 Pfizer/AstraZeneca: Ready for round 2?
Pfizer/AstraZeneca: Ready for round 2?
With the expiration of a three-month period during which Pfizer must stay away from AstraZeneca, under U.K. takeover law, on Tuesday, speculation that the maker of Viagra may eventually seal this deal has risen
8/26 Fast Takes
Unvaccinated Kids Shouldnt Be Allowed in Public Schools; say 79% of SERMO Doctors Polled
Sermo Press Release
J&J Paid Over $150K to Doctor Who Sat on FDA Safety Panels
New Brunswick Today
Zorvolex (diclofenac) Gains New Pain Indication
Fera to Launch Generic Moxatag
Mylan Launches Generic Precedex
8/26 Roche Buys Intermune For $8.3 Bln To Beef Up Specialty Med Portfolio
Roche to buy U.S. biotech firm InterMune for $8.3 billion
world's leading maker of cancer drugs expand into the treatment of rare or incurable diseases
deal brings it a promising new drug, pirfenidone, for treating a progressive and ultimately fatal scarring condition of the lungs. Pirfenidone is approved for so-called idiopathic pulmonary
8/26 Roche Flip-Flops On Decision To Buy Out Chugai
Roche Said to Have Decided Against Bid for Rest of Chugai
owned 62 percent of Chugai as of June 30, was in talks to acquire the rest of the shares for about $10 billion,
dropped those plans after the Japanese drugmaker's management signaled opposition
Roche bought 50 percent of Tokyo-based Chugai in 2002 and boosted the holding to 59.9 percent in 2008.
8/26 Black Box For Antidepressants Turned Out To Be Good Thing
- Antidepressant lawsuits have dried up
'Black box' warning on antidepressants vastly reduced lawsuits against Eli Lilly, others
A once-fertile field of litigation for trial lawyers -- Lilly and other drugmakers once faced hundreds of lawsuits over their antidepressants -- has pretty much dried up. Only a few wrongful-death or injury cases tied to antidepressants remain in U.S. courts
Editor's Note: Only two of the hundreds of Prozac lawsuits ever made it before juries -- and Lilly won both.
8/26 JNJ Settles With Vivus Regarding Topirimate, Walks Away From Lawsuit
- JNJ's patent for using topiramate as weight loss, blood pressure, diabetes pill now officially belongs to Vivis
VIVUS Announces Acquisition of Topiramate-Related Patents From Janssen Pharmaceuticals
VIVUS, announced the acquisition of a group of patents from Janssen covering uses of topiramate as monotherapy and in combination with other pharmaceutical agents to treat a variety of medical conditions
[Vivus Press Release]
8/26 Merck Novel Cancer Drug Looks Like Shoe In
- "Programmed Death Receptor" modulating agent
U.S. approval of Merck cancer immunotherapy expected soon
pembrolizumab would become the first treatment for cancer that blocks a protein called Programmed Death receptor, or PD-1
Bristol-Myers Squibb and Roche Holding AG, are also racing to bring drugs in the same class to market, which analysts say could reach $30 billion in annual sales by 2025
8/25 Fast Takes
Cardiologist Pay Drops For The First Time As Interventions Scrutinized
Ranbaxy Faces $40 Mln (Rs 240 Crore) Fine From State Of Texas
Mylan Launches First Generic Klor-Con® Extended-Release Tabs
Mylan Press Release
8/25 Factoid: Hydrocodone Is The Most Prescribed Drug In The USA
Q: What will happens in October when All hydrocodone goes Schedule II?
A: No Refills, many addicts expected to migrate to heroin
New Rules For Hydrocodone: What You Should Know
Since 2007, more U.S. prescriptions were written for hydrocodone + acetaminophen than any other drug. In 2012, that was over 135 million prescriptions
#2 most prescribed drug is thyroid hormone (levothyroxine sodium), the only other drug to pass 100 million prescriptions in a year
8/25 Ixekizumab: Eli Lilly's Answer To Enbrel Looks Like a Winner
- Experimental data says it's more effective
Lilly psoriasis drug impresses; battle nears with Amgen, Novartis
31 to 41 percent achieved clear skin compared with 5 to 7 percent of those treated with Enbrel
would seek marketing approval in the first half of 2015 for its drug ixekizumab for patients with moderate-to-severe plaque psoriasis
8/25 New Triple Combo Pill For HIV Gets Nod
- "Triumeq" marketed by 3 company joint venture (Glaxo, Pfizer, Shionogi )
Glaxo, Pfizer's ViiV Wins Approval for HIV Combo Drug
combines the integrase strand transfer inhibitor (INSTI) dolutegravir, with the nucleoside reverse transcriptase inhibitors (NRTIs) abacavir and lamivudine
(abacavir 600mg, dolutegravir 50mg and lamivudine 300mg)
8/25 Wal-Mart Goes After CVS MinuteClinic
Wal-Mart Takes Aim at CVS
Wal-Mart's clinics could tempt away CVS patients with low-cost (an office visit costs $40 at a Wal-Mart clinic)
rural markets where there's a shortage of physicians. If that model succeeds, however, Wal-Mart could conceivably move into urban areas and muscle in on CVS' turf everywhere
8/25 Glaxo Gets Nod For Another Elipta Delivered Product; Flutasone; AKA "Arnuity Ellipta"
- Insurers not expected to embrace it
GSK Ellipta franchise expands
doses are Arnuity Ellipta 100mcg and 200mcg
Payers and patients have not strongly taken to the new Ellipta drugs
respiratory unit has been ailing--US respiratory sales fell 14% during the second quarter compared to the same period last year, and by 17% for the first six months of this year